When the Colts take on the Ravens to end Week 5 of the 2021 NFL regular season on "Monday Night Football" (8:15 p.m. ET, ESPN), it will about two teams trying to build on last week's succe s.The Colts (1-3) got their first win by knocking off the Dolphins, while the Ravens (3-1) beat the Broncos, stayinghot since losing to the Raiders in overtime on Monday night in Week 1. The Colts can still win the weak AFC South, while the Ravens need to San Diego Padres keep winning to keep pace in the strong AFC North.Will Carson Wentz continue to get better for Indianapolis? Will Lamar Jackson be further unleashed in the downfield pa sing game for Baltimore?Here's everything to know about betting on Colts vs. Tyson Ross Jersey Ravens in Week 5, including updated odds, trends and our prediction for "Monday Night Football."NFL POWER RANKINGS:Colts vs. Ravens odds for 'MondayNight Football'Spread: Ravens by 7Over/under: 46.5Moneyine:Colts +260, Ravens -360The line has been sitting on a touchdown all week with Baltimore adding a few points to its home-field advantage. Indianapolis won on the road last week. There's some good thought to the total, given the defenses are good enough to keep under 50.(betting odds per)Colts vs. Ravensall-time seriesThe Colts, who relocated from Baltimore, hold a 10-6 advantage. The Ravens have won two in a row, including 24-10 in Indianapolis last season. They also have taken four the past five meetings. Before that, the Colts had taken eight straight games during the Peyton Manning era.Three trends to knowA whopping 86 of spread bettors think the number is too big in favor of the Ravens and like the Colts to cover.53 percent of over/under bettors think the point total is too low given the quarterbacks and defenses that have had a few i sues.The Colts are 5-5 straight up and 5-5 against the spread in their past 10 games. It's split on the overs and unders Dave Winfield Jersey , 5-5. The Ravens are 8-2 SU and 7-3 ATS in their past 10 games, but the total has gone over only 4 times in that span.Three things to watchThe Colts' offensive line injuriesIndianapolis is mi sing the right side of its line again as both guardQuenton Nelson and tackle Braden Smith.remain on the shelf. The Colts will have their hands full with the Ravens' pa s Rickey Henderson Jersey rush and solid run defense up front.The Ravens' new-look pa sing attackBaltimore was dared to throw the ball often in Denver last week and Jackson responded with plenty of downfield strikes, expanding the weaponry at wide receiver and tight end. Jackson should build off that renewed confience at home and it's an important development given the replacement running backs have become le s reliable.The ex-Baltimore factorThe Ravens' fans always get pumped for their team tobeat the Colts, a team that left the citymore than 37 years ago. They should be loud and working to affect the outcome much like the close one against the Chiefsin Week 2.Stats that matter109.7 and 71.1. That's the pa ser rating and average rushing yards per game in Jackson in 12 regular-season night games (8-4 record) with the Ravens. Baltimore did fall in prime time on the road in Week 1, but it did win vs.Kansas Cityon a Sunday night.Colts vs. RavenspredictionThe Colts are overmatched here offensively and defensively. They will have some rushing succe s with Jonathan Taylor, but the Ravens' pre sure and secondary will contain Wentz for most of the game. The Colts have a front seven that can giveJackson a few i sues, but he will his use his moblity and arm to fight through it for a big night.Ravens Cory Spangenberg Jersey 30, Colts 20